Feel free to add your own favorites to this topic.
((Yuko and Rena aren't listed because Yuko would beat all of them and Rena would lose to all of them))
((for "Debut", I listed the recommended game system))
Reiko Kirishima
Debut: Valis (PC-Engine CD)
Pros: Strong-willed, determined, sticks around even after she's dead
Cons: Likes bad boys, once dated a brutal dictator tyrant
Valna
Debut: Valis 2 (PC-Engine CD)
Pros: Wise, gentle, tender
Cons: Very passive and Japanese
Cham
Debut: Valis 3 (PC-Engine CD)
Pros: Tough, survivalist, wild & free personality
Cons: Kleptomaniac
Amu Brande
Debut: Valis 4 (PC-Engine CD)
Pros: Acrobatic, willing to put others before herself
Cons: Tomboyish, ? ((haven't played through Valis 4 yet))
Annet Myers
Debut: El Viento (Sega Genesis)
Pros: Energetic, athletic, multi-talented
Cons: Has a wee bit of a father complex, hangs out with the mafia
Dela Delon
Debut: Brandish (SNES)
Pros: Intelligent, knows how to heat up the situation
Cons: Gets attached to total losers with no social skills... hey, wait a minute, that may not be so bad.
Erim
Debut: Lufia (SNES)
Pros: When she's feeling nice, she is faithful and dedicated, and can cook really well
Cons: When she's not feeling nice, she's a psycho with a god-complex who wants to inflict much pain and suffering upon the world
Lenneth
Debut: Valkyrie Profile (PSX)
Pros: Honest, always interested in a person's whole life (and afterlife)
Cons: Has this nasty tendency to forget the last time you went out with her. Also, her father and older sister are very overprotective.